Buchler Glossary
(Asymmetric) Dihydroxylation
Asymmetric Dihydroxylation of olefins is of high synthetic value because it introduces two vicinal hydroxy groups,...
(Asymmetric) Oxohydroxylation
Asymmetric oxohydroxylation of α-alkyl enoates with potassium permanganate catalyzed by monocationic quaternary...
(Chiral) Organocatalyst
Organocatalysts are one of the bravest attempts to mimic enzyme catalysis that Mother Nature uses. Chiral...
1,2-addition
1,2-addition is a type of organic chemical reaction that involves the addition of functional groups to the 1st and 2nd...
1,4-Addition (conjugate addition)
The Michael reaction is the conjugate 1,4-addition of a resonance stabilized carbanion (michael donor) to an activated...
Aldol Reaction
The aldol reaction unites two carbonyl compounds to form a β-hydroxy-carbonyl product, where one carbonyl compound...
Alkylation
Alkylation is the introduction of an alkyl group into an organic compound by substitution or addition. The alkyl group...
Alkynylation
Alkynylation is an addition reaction in organic synthesis where a terminal alkyne adds to a carbonyl group to form an...
Allylsilylation
An Allylsilylation is performed between allylsilanes and aldehydes furnishes homo allyl alcohols. Using Cinchona...
Aminohydroxylation
The Sharpless Aminohydroxylation allows the syn-selective preparation of 1,2-amino alcohols by reaction of alkenes...
Aromatic System
Any hydrocarbon or heterocycle with 4n+2 electrons in a fully conjugated cyclic π system is considered to be an...
Asymmetric Synthesis (Enantioselective Synthesis)
Asymmetric Synthesis (Enantioselective Synthesis) is the conversion of an achiral substance into a chiral, nonracemic...
Bargellini Reaction
The original reaction (1906) was a mixture of the reagents phenol, chloroform, and acetone in the presence of a sodium...
Barton-Zard Reaction
The Barton–Zard reaction is a route to pyrrole derivatives via the reaction of a nitroalkene with an α-isocyanoacetate...
Betti Reaction
The three-component reaction of aldehydes, primary aromatic amines, and phenols to produce α-aminobenzylphenols is...
Bromination
Bromination is a chemical reaction involving the reaction of a compound and bromine. Finally bromine is being added to...
Cascade Reaction
A cascade reaction, also known as a domino reaction or tandem reaction, is a chemical process that comprises at least...
Chiral Ligand
A chiral ligand is a specially adapted ligand used for asymmetric synthesis. This ligand is an enantiopure organic...
Chiral Phase-Transfer Catalyst (Chiral PTC)
Quaternary ammonium salts, especially derived from Cinchona Alkaloids, have become the most privileged class of chiral...
Chiral Screening Kit
The Buchler chiral screening kit contains a set of slightly different Cinchona alkaloids in very high chemical purity....