Asymmetric Dihydroxylation of olefins is of high synthetic value because it introduces two vicinal hydroxy groups,...
Buchler Glossary
Bargellini Reaction
The original reaction (1906) was a mixture of the reagents phenol, chloroform, and acetone in the presence of a sodium hydroxide solution. Later, organic chemists have used the reaction as a general method of organic synthesis for highly hindered or bulky morpholinones or piperazinones from ketones (particularly acetone) and either β-amino alcohols or diamines. Bargellini reactions have found a widespread use in synthesis.
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