Alkylation is the introduction of an alkyl group into an organic compound by substitution or addition. The alkyl group...
Buchler Glossary
Bargellini Reaction
The original reaction (1906) was a mixture of the reagents phenol, chloroform, and acetone in the presence of a sodium hydroxide solution. Later, organic chemists have used the reaction as a general method of organic synthesis for highly hindered or bulky morpholinones or piperazinones from ketones (particularly acetone) and either β-amino alcohols or diamines. Bargellini reactions have found a widespread use in synthesis.
Further Articles:
Alkynylation
Alkynylation is an addition reaction in organic synthesis where a terminal alkyne adds to a carbonyl group to form an...
Allylsilylation
An Allylsilylation is performed between allylsilanes and aldehydes furnishes homo allyl alcohols. Using Cinchona...
Aminohydroxylation
The Sharpless Aminohydroxylation allows the syn-selective preparation of 1,2-amino alcohols by reaction of alkenes...
Aromatic System
Any hydrocarbon or heterocycle with 4n+2 electrons in a fully conjugated cyclic π system is considered to be an...