Rapid access of 2,3,4-trisubstituted-2,3,4,9-tetrahydrothiopyrano[2,3-b]indole derivatives via one-pot three component reaction using organocatalysis.

Reaction Category:

Henry | Henry | Michael Addition | Sulfa-Michael | Thio-Michael / Henry | Thio-Michael / Henry | Thio-Michael-Henry reaction

Educt:

N-protected-2-chloro-3-formylindole, sodium hydrosulfide, beta-nitrostyrene

Product:

2-aryl-3-nitro-4-hydroxy-2,3,4,9-tetrahydrothiopyrano[2,3-b]indole

Catalyst:

Cupreidine Base

Cas No:

DOI Number:

10.1016/j.tetlet.2012.08.125
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Associated Product from Buchler GmbH:

Cupreidine Base

Cas No:

70877-75-7