Bifunctional squaramide catalysts with the same absolute chirality for the diastereodivergent access to densely functionalised cyclohexanes through enantioselective domino reactions. Synthesis and mechanistic studies.
Reaction Category:
Educt:
ethyl 2-nitropropanoate, (E)-(2-nitrovinyl)benzene
Product:
ethyl (2S,3R)-2-methyl-2,4-dinitro-3-phenylbutanoate, ethyl (2R,3R)-2-methyl-2,4-dinitro-3-phenylbutanoate
Catalyst:
3-((3,5-bis(trifluoromethyl)benzyl)amino)-4-(((R)-(6-methoxyquinolin-4-yl)((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methyl)amino)cyclobut-3-ene-1,2-dione
Cas No:
1073917-09-5
DOI Number:
10.1002/adsc.201400502
Associated Product from Buchler GmbH:
Quinidine Base
Cas No:
56-54-2