Highly Enantioselective Organocatalytic Hydroxyalkylation of Indoles with Ethyl Trifluoropyruvate

Reaction Category:

Further reactions | Hydroxyalkylation

Educt:

1H-indole, ethyl 3,3,3-trifluoro-2-oxopropanoate

Product:

ethyl (S)-3,3,3-trifluoro-2-hydroxy-2-(1H-indol-3-yl)propanoate

Catalyst:

Cinchonidine Base

Cas No:

DOI Number:

10.1002/anie.200462877
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Associated Product from Buchler GmbH:

Cinchonidine Base

Cas No:

485-71-2