Highly enantioselective asymmetric Henry reaction catalyzed by novel chiral phase transfer catalysts derived from cinchona alkaloids

Reaction Category:

Henry | Henry with nitromethane | Henry with nitromethane

Educt:

4-Methylbenzaldehyde, Nitromethane

Product:

(R)-2-nitro-1-p-tolylethanol

Catalyst:

Cinchonanium, 1,1''-[[(1E,4E)-3-oxo-1,4-pentadiene-1,5-diyl]bis(4,1-phenylenemethylene)]bis[9-(2-propen-1-yloxy)-, bromide (1:2), (9S)-(9''S)-

Cas No:

2023815-77-0; 2023815-79-2

DOI Number:

10.1039/c6ob01687a
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Associated Product from Buchler GmbH:

Cinchonine Base

Cas No:

118-10-5